I. ROLE OF THE INNATE AND ADAPTIVE IMMUNITY FOR A DEVELOPMENT OF DESTRUCTIVE IMMUNE RESPONSE OF ORGANISM ON ALLOGRAFT

Abstract

It is known, transplantation of organs is accompanied by activation of adaptive immunity (cellular and humoral) and innate immunity in an organism of the recipient. Population of T-lymphocyte which includes some subpopu- lations of cells , such as Тcyt, Th1, Th2 and T-regulatory cells, first of all responsible for development of these forms of the immune answer. The actual problem of modern transplantology is working out of methods which would promote accumulation in an organism of recipient T-regulatory of cells with suppressive properties for formation the donor-specific immune tolerance into recipient`s organism.

Keywords

• innate immunity
• adaptive immunity
• organ transplantation
• t-regulatory cells
• transplantation tolerance.