Bulletin of Faculty of Pharmacy Cairo University (Jun 2015)

Naturally occurring didemnaketals: Structural elucidation, features, and pharmacological activities

  • Gamal A. Mohamed,
  • Sabrin R. M. Ibrahim,
  • Diaa T. A. Youssef

DOI
https://doi.org/10.1016/j.bfopcu.2015.02.003
Journal volume & issue
Vol. 53, no. 1
pp. 69 – 76

Abstract

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Didemnaketals are rare terpenoid class reported only in the marine ascidian Didemnum species. They possess important biological activities like HIV-1 protease inhibitor, protein kinase inhibition, antimicrobial, antiproliferative, and cytotoxic. A compilation of new naturally occurring didemnaketals reported during 1991–2014 is provided with available physical and spectral data: mp, [α]D, UV, IR, 1H and 13C NMR as well as biological activities and references.

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