Nature Communications (Nov 2021)

Electrochemical C–N bond activation for deaminative reductive coupling of Katritzky salts

  • Yeqing Liu,
  • Xiangzhang Tao,
  • Yu Mao,
  • Xin Yuan,
  • Jiangkai Qiu,
  • Linyu Kong,
  • Shengyang Ni,
  • Kai Guo,
  • Yi Wang,
  • Yi Pan

DOI
https://doi.org/10.1038/s41467-021-27060-7
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 7

Abstract

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Electrochemical transformations use electrons and electron holes instead of chemical oxidants and reductants as reagents. Here, the authors report an electrochemical reductive deaminative cross-coupling of Katrizky salts with various radical acceptors, including examples of fluoroalkenylation, alkynylation and thiolation.