Antimicrobial resistance in pediatric patients with urinary infections

Abstract

Background: the treatment of bacterial infections has become a very complex phenomenon due to the severity of some diseases, the bacterial resistance increase and the notable decrease in the appearance of new antibacterial agents. Objective: to describe the antimicrobial resistance of the strains of microorganisms isolated in the urine cultures taken at the Microbiology Laboratory of the Pediatric Hospital of the province of Las Tunas, during 2020. Method: an observational, descriptive, cross-sectional study was carried out with the 2670 urine cultures taken at the aforementioned laboratory and during the period herein stated. The results of the cultures, the isolated germs and the antimicrobial resistance were assessed. The data were processed according to descriptive statistics. Results: 477 samples were positive (17,87 %) with performed antibiogram, having a predominance of Gram-negative bacteria (88,02 %). E coli represented 69,50 %, followed by Klebsiella spp (12,85 %) and Staphylococcus spp (8,28 %). In Gram-positive bacteria, resistance to ceftazidime stood out (66,67 %), amoxicillin (37,93 %), amikacin (36,0 %), amoxicillin/clavulanic acid (35,39 %) and ceftriaxone (35,0). E coli showed resistance values higher than 50 % (amoxicillin 88,50 %, doxycycline 66,44 %, nalidixic acid 64,74 %, amoxicillin/clavulanic acid 52.63%, and ciprofloxacin 50,65 %). Klebsiella spp had very high figures for amoxicillin (93,54 %) and Staphylococcus spp for ceftazidime (78,57 %), ceftriaxone (44,44 %) and meropenem (44,44 %). Conclusions: the antimicrobial resistance of the microorganisms isolated in the urine cultures was described.

Keywords

• farmacorresistencia microbiana
• infecciones bacterianas
• pediatría
• infecciones urinarias