Screening for aneuploidies in first trimester: Overview and patient management

Abstract

Introduction: First trimester prenatal screening is a risk assessment test which allows to detect pregnancies at increased risk for for most frequent foetal aneuploidies. Methods: A literature review using PubMed was carried out. Results: In this review, we focus on general principles of first trimester screening, assessment of specific sonographic markers and maternal biochemical parameters. In addition, management options are discussed.

Keywords

• aneuploidies
• nuchal translucency
• obstetrics and gynaecology
• ultrasound sonography