Neonatal lupus

Abstract

Neonatal lupus (NL) is a syndrome diagnosed in neonatal infants, whose mothers frequently suffer from autoimmune rheumatic diseases, manifested by two major signs: skin lesion and cardiac lesion. The paper gives data from the history of a description of the syndrome, as well as current ideas on its pathogenesis, considers both typical and rarer clinical manifestations of the disease, and presents approaches to NL therapy and prevention.

Keywords

• неонатальная волчанка
• ro/ssa- и la/ssb-антитела
• поражение кожи
• врожденная блокада сердца