Dataset of allele, genotype and haplotype frequencies of four LIN28B gene polymorphisms analyzed for association with age at menarche in Russian women
Irina Ponomarenko,
Evgeny Reshetnikov,
Oleg Golovchenko,
Alexey Polonikov,
Irina Verzilina,
Inna Sorokina,
Inna Aristova,
Anna Yermachenko,
Volodymyr Dvornyk,
Mikhail Churnosov
Affiliations
Irina Ponomarenko
Department of Medical Biological Disciplines, Belgorod State University, 308015, Belgorod, Russia
Evgeny Reshetnikov
Department of Medical Biological Disciplines, Belgorod State University, 308015, Belgorod, Russia; Corresponding author.
Oleg Golovchenko
Department of Obstetrics and Gynecology, Belgorod State University, 308015, Belgorod, Russia
Alexey Polonikov
Department of Biology, Medical Genetics and Ecology, Kursk State Medical University, 305041, Kursk, Russia
Irina Verzilina
Department of Medical Biological Disciplines, Belgorod State University, 308015, Belgorod, Russia
Inna Sorokina
Department of Medical Biological Disciplines, Belgorod State University, 308015, Belgorod, Russia
Inna Aristova
Department of Medical Biological Disciplines, Belgorod State University, 308015, Belgorod, Russia
Anna Yermachenko
Department of Social Epidemiology, Pierre Louis Institute of Epidemiology and Public Health, 75571, Paris, France; Sorbonne Universités, 75320, Paris, France
Volodymyr Dvornyk
Department of Life Sciences, College of Science and General Studies, Alfaisal University, 11533, Riyadh, Saudi Arabia
Mikhail Churnosov
Department of Medical Biological Disciplines, Belgorod State University, 308015, Belgorod, Russia
In this paper, we present the allele, genotype and haplotype frequencies of 4 single nucleotide polymorphisms (SNPs) in LIN28B gene (rs4946651, rs7759938, rs314280, rs314276) in a sample of Russian women. These SNPs had been previously identified to be associated with age at menarche in genome-wide association studies (GWAS). The information about age at menarche was obtained using the questionnaire. The frequencies of alleles, genotypes and haplotypes of four SNPs were classified in 3 groups: the whole sample, individuals with the early age at menarche (<12 years), and those with the average age at menarche (12–14 years). Keywords: LIN28B gene, Single nucleotide polymorphism, Age at menarche
