Data on a rat infection model to assess porous titanium implant coatings
M. Croes,
H. de Visser,
B.P. Meij,
K. Lietart,
B.C.H. van der Wal,
H.C. Vogely,
A.C. Fluit,
C.H.E. Boel,
J. Alblas,
H. Weinans,
S. Amin Yavari
Affiliations
M. Croes
Department of Orthopedics, University Medical Center Utrecht, Utrecht, the Netherlands
H. de Visser
Department of Orthopedics, University Medical Center Utrecht, Utrecht, the Netherlands
B.P. Meij
Department of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, Utrecht, the Netherlands
K. Lietart
3D Systems - LayerWise NV, Leuven, Belgium; Department of Metallurgy and Materials Engineering, KU Leuven, Leuven, Belgium
B.C.H. van der Wal
Department of Orthopedics, University Medical Center Utrecht, Utrecht, the Netherlands
H.C. Vogely
Department of Orthopedics, University Medical Center Utrecht, Utrecht, the Netherlands
A.C. Fluit
Department of Medical Microbiology, University Medical Center Utrecht, Utrecht, the Netherlands
C.H.E. Boel
Department of Medical Microbiology, University Medical Center Utrecht, Utrecht, the Netherlands
J. Alblas
Department of Orthopedics, University Medical Center Utrecht, Utrecht, the Netherlands
H. Weinans
Department of Orthopedics, University Medical Center Utrecht, Utrecht, the Netherlands; Department of Biomechanical Engineering, Delft University of Technology, Delft, the Netherlands; Department of Rheumatology, University Medical Center Utrecht, Utrecht, the Netherlands
S. Amin Yavari
Department of Orthopedics, University Medical Center Utrecht, Utrecht, the Netherlands; Corresponding author.
A model is needed to study the effectiveness of different anti-bacterial coatings on complex metal implants in a bone environment. This article shares data on the design of porous titanium implants for intramedullary implantation in the proximal rat tibia. The implant length, diameter and porosity were optimized after testing on cadaveric specimens. This article shares data on which parameters are critical to establish a chronic implant infection in Sprague Dawley rats when using the new implant design. To this end, different strains of Staphylococcus aureus and inoculation doses were investigated.
