E-Journal of Chemistry (Jan 2010)

An Efficient Solvent-Free Protocol for the Synthesis of 1-Amidoalkyl-2-naphthols using Silica-Supported Molybdatophosphoric Acid

  • Abdolkarim Zare,
  • Alireza Hasaninejad,
  • Esmael Rostami,
  • Ahmad Reza Moosavi-Zare,
  • Nasrin Pishahang,
  • Mehrnoosh Roshankar,
  • Fatemeh Khedri,
  • Maasoomeh Khedri

DOI
https://doi.org/10.1155/2010/512392
Journal volume & issue
Vol. 7, no. 4
pp. 1162 – 1169

Abstract

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A highly efficient, green and simple solvent-free method for the synthesis of 1-amidoalkyl-2-naphthols via one-pot multi-components condensation of 2-naphthol, aromatic aldehydes and amides in the presence of catalytic amount of silica-supported molybdatophosphoric acid (H3PMo12O40.xH2O/SiO2, 3.17 mol%) is described. The reactions proceed rapidly and the title compounds are produced in high to excellent yields.