Nature Communications (Jul 2022)
Immune responses in Omicron SARS-CoV-2 breakthrough infection in vaccinated adults
- Hassen Kared,
- Asia-Sophia Wolf,
- Amin Alirezaylavasani,
- Anthony Ravussin,
- Guri Solum,
- Trung The Tran,
- Fridtjof Lund-Johansen,
- John Torgils Vaage,
- Lise Sofie Nissen-Meyer,
- Unni C. Nygaard,
- Olav Hungnes,
- Anna H. Robertson,
- Lisbeth Meyer Næss,
- Lill Trogstad,
- Per Magnus,
- Ludvig A. Munthe,
- Siri Mjaaland
Affiliations
- Hassen Kared
- KG Jebsen Centre for B cell malignancy, Institute of Clinical medicine, University of Oslo
- Asia-Sophia Wolf
- Division of Infection Control, Norwegian Institute of Public Health
- Amin Alirezaylavasani
- KG Jebsen Centre for B cell malignancy, Institute of Clinical medicine, University of Oslo
- Anthony Ravussin
- Division of Infection Control, Norwegian Institute of Public Health
- Guri Solum
- Division of Infection Control, Norwegian Institute of Public Health
- Trung The Tran
- Department of Immunology, Oslo University Hospital
- Fridtjof Lund-Johansen
- Department of Immunology, Oslo University Hospital
- John Torgils Vaage
- Department of Immunology, Oslo University Hospital
- Lise Sofie Nissen-Meyer
- Department of Immunology, Oslo University Hospital
- Unni C. Nygaard
- Division of Infection Control, Norwegian Institute of Public Health
- Olav Hungnes
- Division of Infection Control, Norwegian Institute of Public Health
- Anna H. Robertson
- Division of Infection Control, Norwegian Institute of Public Health
- Lisbeth Meyer Næss
- Division of Infection Control, Norwegian Institute of Public Health
- Lill Trogstad
- Division of Infection Control, Norwegian Institute of Public Health
- Per Magnus
- Center for Fertility and Health, Norwegian Institute of Public Health
- Ludvig A. Munthe
- KG Jebsen Centre for B cell malignancy, Institute of Clinical medicine, University of Oslo
- Siri Mjaaland
- Division of Infection Control, Norwegian Institute of Public Health
- DOI
- https://doi.org/10.1038/s41467-022-31888-y
- Journal volume & issue
-
Vol. 13,
no. 1
pp. 1 – 12
Abstract
The SARS-CoV-2 Omicron variant possess many mutations within the receptor binding domain of the Spike protein, which confer increased transmissibility and higher antibody escape. Here, the authors carry out analysis of the serological and cellular immune responses of individuals with Omicron breakthrough infection.
