Invasive Aspergillus flavus sinusitis in an immunocompetent patient using intranasal cocaine
Lauren Bougioukas,
Brendan Campbell,
Kyle Crooker,
Jason A. Freed,
Jonathan Wilcock,
Devika Singh,
Andrew J. Hale
Affiliations
Lauren Bougioukas
Larner College of Medicine, University of Vermont, Burlington, VT, United States
Brendan Campbell
University of Vermont Medical Center, Burlington, VT, United States
Kyle Crooker
University of Vermont Medical Center, Burlington, VT, United States
Jason A. Freed
Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States
Jonathan Wilcock
University of Vermont Medical Center, Burlington, VT, United States
Devika Singh
Larner College of Medicine, University of Vermont, Burlington, VT, United States; University of Vermont Medical Center, Burlington, VT, United States
Andrew J. Hale
Larner College of Medicine, University of Vermont, Burlington, VT, United States; University of Vermont Medical Center, Burlington, VT, United States; Correspondence to: University of Vermont Medical Center, Infectious Disease Unit, 111 Colchester Avenue, Mailstop 115 SM2, Burlington, VT 05401, United States.
Invasive fungal sinusitis is a rare and potentially fatal infection that tends to occur in immunocompromised hosts. Presented is the case of a 33-year-old immunocompetent male with several months of recurrent facial and nasal pain refractory to several antibacterial courses before a diagnosis of invasive Aspergillus sinusitis was made. The patient’s symptoms and infection were successfully treated with a combination of surgical debridement and voriconazole. The authors review the epidemiology, risk factors, diagnosis, and treatment of invasive fungal sinusitis due to Aspergillus.
