Case Report: Activated PI3-kinase-δ syndrome and ovarian malignancies: a case series from the European ESID-APDS registry

• Maria Pia Esposto,
• Nizar Mahlaoui,
• Nizar Mahlaoui,
• Hassan Abolhassani,
• Hassan Abolhassani,
• Koen Van Aerde,
• Simone Cesaro,
• Anita Chandra,
• Anita Chandra,
• Stephan Ehl,
• Sven Kracker,
• Felipe Suarez,
• Felipe Suarez,
• Vincent Barlogis,
• Vincent Barlogis,
• Vincent Barlogis,
• Alice Parisi,
• Maria Elena Maccari,
• Maria Elena Maccari,
• Matteo Chinello

Affiliations

Maria Pia Esposto

Pediatric Hematology Oncology, Department of Mother and Child, Azienda Ospedaliera Universitaria Integrata Verona, Verona, Italy

Nizar Mahlaoui

Pediatric Immuno-Haematology and Rheumatology Unit, Necker Enfants Malades University Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France

Nizar Mahlaoui

French National Reference Center for Primary Immune Deficiencies (CEREDIH), Necker Enfants Malades University Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France

Hassan Abolhassani

Division of Immunology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden

Hassan Abolhassani

Research Center for Immunodeficiencies, Pediatrics Center of Excellence, Children’s Medical Center, Tehran University of Medical Sciences, Tehran, Iran

Koen Van Aerde

Department of pediatric infectious disease and immunology, Amalia Children’s Hospital, Radboudumc, Nijmegen, Netherlands

Simone Cesaro

Pediatric Hematology Oncology, Department of Mother and Child, Azienda Ospedaliera Universitaria Integrata Verona, Verona, Italy

Anita Chandra

Department of Clinical Immunology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom

Anita Chandra

Department of Medicine, University of Cambridge, Cambridge, United Kingdom

Stephan Ehl

Institute for Immunodeficiency, Center for Chronic Immunodeficiency, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany

Sven Kracker

0Laboratory of Lymphocyte Activation and Susceptibility to Epstein Barr Virus (EBV) infection, Imagine Institute, INSERM UMR 1163, Université Paris Cité, Paris, France

Felipe Suarez

1Université Paris Cité, Inserm U-1163, Institut Imagine, Laboratoire of Hematological Disorders, Paris, France

Felipe Suarez

2Service d’Hématologie Adulte and Centre de référence des déficits immunitaires héréditaires (CEREDIH), AP-HP, Hôpital Necker-Enfants Malades, Paris, France

Vincent Barlogis

3Department of Pediatric Hematology, Immunology and Oncology, APHM, Hôpital de la Timone Enfants, Marseille, France

Vincent Barlogis

4CEReSS Research Unit EA 3279 and Department of Public Health, Aix Marseille University, School of Medicine, Marseille, France

Vincent Barlogis

5Aix Marseille University, School of Medicine, Marseille, France

Alice Parisi

6Department of Pathological Anatomy, Azienda Ospedaliera Universitaria Integrata Verona, Verona, Italy

Maria Elena Maccari

Institute for Immunodeficiency, Center for Chronic Immunodeficiency, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany

Maria Elena Maccari

7Department of Pediatric Hematology, Oncology and Stem Cell Transplantation, Children’s Hospital, Medical Center – University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany

Matteo Chinello

Pediatric Hematology Oncology, Department of Mother and Child, Azienda Ospedaliera Universitaria Integrata Verona, Verona, Italy