Value of placental volume combined with GLUT3 in predicting fetal growth restriction

Abstract

Objective To analyze the value of placental volume combined with serum glucose transporter 3 (GLUT3) in predicting fetal growth restriction. Methods One hundred pregnant women with fetal growth restriction who underwent MRI examination in our hospital from December 2018 to May 2020 were selected as observation group, and 100 normal pregnant women as control group. The placental volumes of the subjects were measured by MRI examination, and the serum GLUT3 level was mea-sured. The combined diagnosis model of placental volume and serum GLUT3 level was established by logistic regression model. The area under the receiver operating characteristic curve (AUC) was applied to evaluate the value of placental volume and serum GLUT3 level used alone or in combination in predicting fetal growth restriction. Results There were significant differences in placental volume and serum GLUT3 level between the observation group and the control group (t=13.380,54.173,P<0.05). The model of fetal growth restriction predicted by placental volume combined with serum GLUT3 level was Logit (P)=-0.647×placental volume+0.598×GLUT+0.431. The sensitivity, specificity, and AUC of placental volume combined with serum GLUT3 level in predicting fetal growth restriction were significantly higher than those of placental volume or serum GLUT3 level alone (P<0.05). Conclusion Placental volume combined with serum GLUT3 level has a certain predictive value for fetal growth restriction.

Keywords

• placental volume|glucose transporter type 3|fetal growth retardation|forecasting|magnetic resonance imaging