Symptomatic creatine phosphokinase elevation in a Crohn's disease patient caused by upadacitinib

Abstract

Key Clinical Message We present a Crohn's disease patient receiving high dose upadacitinib treatment with elevated CPK levels and myopathy, and provide the reader with practical tips on stopping and restarting upadacitinib, emphasizing the need for adequate monitoring.

Keywords

• CPK elevation
• Crohn's disease
• myopathy
• upadacitinib