Electrophysiological and genetic aspects of predisposition to development of paroximal av node reentry tachycardia. The role of connexin

Abstract

In the last decade developing of human's molecular genetics has also touched genetic aspects of regulation and functioning of heart conducting system. The complex analysis of comparison of the genetic and clinical data shows the existence of a direct link between the genetic defect, features of a clinical picture and the forecast of disease. Fibers of connexin which are now examined as one of the key molecular substrate of intercellular pulse transmitters represent a particular interest in this area.

Keywords

• пароксизмальная реципрокная АВ узловая тахикардия
• коннексины
• генетика человека
• гены-кандидаты