Zhongguo quanke yixue (Sep 2022)
Application of Two Scoring Systems in Prediction of Postoperative Complications after Radical Resection of Colorectal Cancer
Abstract
Background Colorectal cancer is a common tumor, and surgery is still one of the main treatment methods. Nowadays the research on surgical treatment of colorectal cancer is very mature, but that of predicting the possibilities of postoperative complications from preoperative and intraoperative status is scarce. Objective To investigate the predictive value of POSSUM system and aCCI index in postoperative complications after radical resection of colorectal cancer. Methods Retrospective analysis was performed on the clinical data of 118 patients performed colorectal cancer operation in the First Hospital of Hebei Medical University from June 2016 to September 2020. They were divided into complication group (n=42) and non-complication group (n=76) according to the incidence of postoperative complications. Spearman rank correlation was used to explore the relationship between postoperative complications after radical resection of colorectal cancer and clinical indicators. ROC curve was used to evaluate the predictive value of POSSUM system and aCCI index. Results R1, R2, aCCI levels and blood loss in the complication group were higher than those in the non-complication group, while Z and preoperative Hb levels were lower than those in the non-complication group (P<0.05) . TNM staging ratois were compared in the two groups, and the difference was statistically significant (P<0.05) . R1, R2 and Z were predicted to be 0.065 (0.039, 0.131) , 0.349 (0.220, 0.585) and 0.775 (0.214, 0.901) within 30 days. 36.1% (42/118) developed postoperative complications within 30 days after operation, and 1.7% (2/118) died of anastomotic leakage. Postoperative complications were positively correlated with TNM stage and blood loss, and negatively correlated with preoperative Hb (P<0.05) . The area under ROC curve (AUC) of R1, R2 and aCCI indexes for predicting postoperative complications after radical resection of colorectal cancer were 0.727, 0.728 and 0.638, the optimal cut-off values were 0.114, 0.516 and 3.500, the sensitivities were 57.1%, 57.1% and 52.4% respectively, the specificity was 81.6%, 80.3% and 65.8% respectively. Conclusion Both POSSUM system and aCCI index have predictive value for the occurrence of complications after radical resection of colorectal cancer and can be used in clinical decision.
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