Nature Communications (Jun 2022)

Coupling of growth rate and developmental tempo reduces body size heterogeneity in C. elegans

  • Klement Stojanovski,
  • Helge Großhans,
  • Benjamin D. Towbin

DOI
https://doi.org/10.1038/s41467-022-29720-8
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 14

Abstract

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Animals must reach the correct size during development, despite stochastic differences in their growth rate. Here, Stojanovski et al. show that a coupling of growth and development by an oscillatory timer buffers fluctuations in the growth of the nematode C. elegans to ensure its correct size.