The Host–Pathogen Interplay: A Tale of Two Stories within the Cornea and Posterior Segment

Abstract

Ocular infectious diseases are an important cause of potentially preventable vision loss and blindness. In the following manuscript, we will review ocular immunology and the pathogenesis of herpesviruses and Pseudomonas aeruginosa infections of the cornea and posterior segment. We will highlight areas of future research and what is currently known to promote bench-to-bedside discoveries to improve clinical outcomes of these debilitating ocular diseases.

Keywords

• acute retinal necrosis
• innate immunity
• ocular immunology
• immune privilege
• HSV-1
• keratitis