Dosimetric Analysis of Template-assisted 192Ir-source Hypofractionated Stereotactic Ablative Brachytherapy for Peripheral Lung Cancer

Abstract

Objective To explore the dose of template-assisted 192Ir source hypofractionated stereotactic brachytherapy (SABT) for peripheral lung cancer. Methods We retrospectively analyzed the dose parameters of GTV and OARs of 28 peripheral lung cancer patients treated with template-assisted 192Ir-source hypofractionated SABT, and compared the dose parameters between SABT with virtual SBRT. Results The Dmean and V150 for the GTV in the SABT plan were significantly higher than those in the SBRT plan (all P 0.05). Conclusion Template-assisted 192Ir source hypofractionated SABT ensures high dose in the gross tumor volume and reduces the dose in organs at risk in the treatment of peripheral lung cancer.

Keywords

• stereotactic ablative brachytherapy
• 192ir-source
• peripheral lung cancer
• stereotactic body radiation therapy