Digestive Diseases in the Structure of Somatic Pathology in Adolescents with Nontoxic Diffuse Goiter

Abstract

145 girls and 177 boys aged 10–17 years were examined to determine a place of digestive diseases in the structure of somatic pathology in adolescents with nontoxic diffuse goiter. Thyroid ultrasound has been carried out, concentrations of thyroid-stimulating hormone and free fractions of thyroid hormones have been measured. To diagnose concomitant somatic pathology, the authors have performed an extensive complex examination with determination of blood lipids. It is found that most adolescents (87.0 %) had two or more concomitant somatic diseases. Chronic digestive pathology has been detected in 81.5 % of patients, with domination of functional disorders of the gallbladder by a hypotonic type (76.3 %). In adolescents with goiter, we have diagnosed pathological changes in blood lipids due to increased concentrations of beta-lipoproteins (51.9 %), total cholesterol (39.9 %) and low-density lipoprotein cholesterol (23.7 %), which are most characteristic of patients with unfavorable course of thyropathy. Our study has confirmed a close relationship between the blood lipids and thyroid profile.

Keywords

• adolescents
• nontoxic diffuse goiter
• digestive diseases