Biomedicines (Jan 2024)

Short- and Long-Term Outcomes of Patients with Postoperative Arrhythmia after Liver Surgery

  • Felix Rühlmann,
  • Deborah Engelhardt,
  • Alma Franziska Mackert,
  • Mara Sophie Hedicke,
  • Tobias Tichelbäcker,
  • Andreas Leha,
  • Markus Bernhardt,
  • Michael Ghadimi,
  • Thorsten Perl,
  • Azadeh Azizian,
  • Jochen Gaedcke

DOI
https://doi.org/10.3390/biomedicines12020271
Journal volume & issue
Vol. 12, no. 2
p. 271

Abstract

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Background: New-onset postoperative arrhythmia (PA) has previously been described as a pivotal risk factor for postoperative morbidity and mortality after visceral surgery. However, there is a lack of data concerning liver surgery. The incidence and impact of new-onset postoperative arrhythmia after liver surgery was, therefore, analyzed in a monocentric study. Methods: In total, n = 460 patients (221 female, 239 male) who underwent liver surgery between January 2012 and April 2020 without any prior arrhythmia in their medical history were included in this retrospective analysis. Clinical monitoring started with the induction of anesthesia and was terminated with discharge from the intensive care unit (ICU) or intermediate care unit (IMC). Follow-up included documentation of complications during the hospital stay, as well as long-term survival analysis. Results: Postoperative arrhythmia after liver surgery was observed in 25 patients, corresponding to an incidence of 5.4%. The occurrence of arrhythmia was significantly associated with intraoperative complications (p p p p p < 0.001). Conclusions: New-onset postoperative arrhythmia after liver surgery has an incidence of only 5.4% but is significantly associated with higher postoperative morbidity and poorer overall survival.

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