Multipotent human stromal cells isolated from cord blood, term placenta and adult bone marrow show distinct differences in gene expression pattern

Nicholas Matigian; Gary Brooke; Faten Zaibak; Tony Rossetti; Katarina Kollar; Rebecca Pelekanos; Celena Heazlewood; Alan Mackay-Sim; Christine A. Wells; Kerry Atkinson

doi:10.1016/j.gdata.2014.11.011

Genomics Data (Mar 2015)

Multipotent human stromal cells isolated from cord blood, term placenta and adult bone marrow show distinct differences in gene expression pattern

Nicholas Matigian,
Gary Brooke,
Faten Zaibak,
Tony Rossetti,
Katarina Kollar,
Rebecca Pelekanos,
Celena Heazlewood,
Alan Mackay-Sim,
Christine A. Wells,
Kerry Atkinson

Affiliations

Nicholas Matigian: Australian Institute for Bioengineering and Nanotechnology, University of Queensland, Brisbane, 4072, Australia
Gary Brooke: Mater Medical Research Institute, University of Queensland, Woolloongabba, Brisbane, 4102, Australia
Faten Zaibak: Murdoch Children's Research Institute, The University of Melbourne, Royal Children's Hospital, Parkville, Victoria, 3052, Australia
Tony Rossetti: Mater Medical Research Institute, University of Queensland, Woolloongabba, Brisbane, 4102, Australia
Katarina Kollar: Mater Medical Research Institute, University of Queensland, Woolloongabba, Brisbane, 4102, Australia
Rebecca Pelekanos: Mater Medical Research Institute, University of Queensland, Woolloongabba, Brisbane, 4102, Australia
Celena Heazlewood: Mater Medical Research Institute, University of Queensland, Woolloongabba, Brisbane, 4102, Australia
Alan Mackay-Sim: Eskitis Institute for Drug Discovery, National Centre for Adult Stem Cell Research, Griffith University, Brisbane, 4111, Australia
Christine A. Wells: Australian Institute for Bioengineering and Nanotechnology, University of Queensland, Brisbane, 4072, Australia
Kerry Atkinson: Mater Medical Research Institute, University of Queensland, Woolloongabba, Brisbane, 4102, Australia

DOI: https://doi.org/10.1016/j.gdata.2014.11.011
Journal volume & issue: Vol. 3, no. C
pp. 70 – 74

Abstract

Read online

Multipotent mesenchymal stromal cells derived from human placenta (pMSCs), and unrestricted somatic stem cells (USSCs) derived from cord blood share many properties with human bone marrow-derived mesenchymal stromal cells (bmMSCs) and are currently in clinical trials for a wide range of clinical settings. Here we present gene expression profiles of human cord blood-derived unrestricted somatic stem cells (USSCs), human placental-derived mesenchymal stem cells (hpMSCs), and human bone marrow-derived mesenchymal stromal cells (bmMSCs), all derived from four different donors. The microarray data are available on the ArrayExpress database (www.ebi.ac.uk/arrayexpress) under accession number E-TABM-880. Additionally, the data has been integrated into a public portal, www.stemformatics.org. Our data provide a resource for understanding the differences in MSCs derived from different tissues.

Published in Genomics Data

ISSN: 2213-5960 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Science: Biology (General): Genetics
Website: http://www.journals.elsevier.com/genomics-data/

About the journal

Abstract

Keywords