Redox Experimental Medicine (Jul 2024)

Effects of anti-aging redox medicine on health span and lifespan

  • Giuseppe Poli,
  • Enrique Cadenas,
  • Ettore Bologna

DOI
https://doi.org/10.1530/REM-24-0006
Journal volume & issue
Vol. 2024, no. 1
pp. 1 – 3

Abstract

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Anti-aging redox medicine is a field focused on addressing the effects of aging by targeting cellular redox (reduction–oxidation) processes, which play crucial roles in various biological functions. Redox processes involve the transfer of electrons between molecules, and maintaining their balance is essential for cellular health and function. With age, these processes tend to become dysregulated, leading to increased oxidative stress and damage, which are associated with age-related diseases and a decline in physiological functions. Some research suggests that interventions targeting redox signaling pathways could slow down the aging process at a molecular level. By promoting cellular repair mechanisms and reducing the accumulation of damage, these interventions may help delay age-related decline of physiological functions and extend lifespan. Indeed, many age-related diseases are associated with oxidative stress and dysregulated redox signaling. By addressing these underlying mechanisms, anti-aging redox medicine may help prevent or delay the onset of conditions such as cardiovascular disease, Alzheimer’s disease, and cancer, thereby extending health span.