Self-replication of DNA by its encoded proteins in liposome-based synthetic cells

Pauline van Nies; Ilja Westerlaken; Duco Blanken; Margarita Salas; Mario Mencía; Christophe Danelon

doi:10.1038/s41467-018-03926-1

Nature Communications (Apr 2018)

Self-replication of DNA by its encoded proteins in liposome-based synthetic cells

Pauline van Nies,
Ilja Westerlaken,
Duco Blanken,
Margarita Salas,
Mario Mencía,
Christophe Danelon

Affiliations

Pauline van Nies: Department of Bionanoscience, Kavli Institute of Nanoscience, Delft University of Technology
Ilja Westerlaken: Department of Bionanoscience, Kavli Institute of Nanoscience, Delft University of Technology
Duco Blanken: Department of Bionanoscience, Kavli Institute of Nanoscience, Delft University of Technology
Margarita Salas: Centro de Biología Molecular “Severo Ochoa” (CSIC-UAM), Universidad Autónoma
Mario Mencía: Centro de Biología Molecular “Severo Ochoa” (CSIC-UAM), Universidad Autónoma
Christophe Danelon: Department of Bionanoscience, Kavli Institute of Nanoscience, Delft University of Technology

DOI: https://doi.org/10.1038/s41467-018-03926-1
Journal volume & issue: Vol. 9, no. 1
pp. 1 – 12

Abstract

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Replicating DNA and converting genetic information to protein is a feature of cellular life. Here the authors implement a coupled DNA replication and gene expression system inside vesicles.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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