Dissecting cell-type-specific roles of androgen receptor in prostate homeostasis and regeneration through lineage tracing

Qing Xie; Yueli Liu; Tao Cai; Corrigan Horton; Joshua Stefanson; Zhu A. Wang

doi:10.1038/ncomms14284

Nature Communications (Jan 2017)

Dissecting cell-type-specific roles of androgen receptor in prostate homeostasis and regeneration through lineage tracing

Qing Xie,
Yueli Liu,
Tao Cai,
Corrigan Horton,
Joshua Stefanson,
Zhu A. Wang

Affiliations

Qing Xie: Department of Molecular, Cell and Developmental Biology, University of California
Yueli Liu: Department of Molecular, Cell and Developmental Biology, University of California
Tao Cai: Sequencing Center, National Institute of Biological Sciences
Corrigan Horton: Department of Molecular, Cell and Developmental Biology, University of California
Joshua Stefanson: Department of Molecular, Cell and Developmental Biology, University of California
Zhu A. Wang: Department of Molecular, Cell and Developmental Biology, University of California

DOI: https://doi.org/10.1038/ncomms14284
Journal volume & issue: Vol. 8, no. 1
pp. 1 – 14

Abstract

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Androgen receptor is an important regulator of prostate development and cancer. In this study, the authors use genetic lineage tracing in mice to clarify the role of AR in different prostate epithelial cells.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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