What’s the burden of osteoporosis on Egyptian patients with chronic obstructive pulmonary disease?

Abstract

Background Chronic obstructive pulmonary disease (COPD) is a complex disease, where the initial symptoms are often cough and dyspnea. patients with moderate to severe COPD have often multiorganic disease and a decreased quality of life. Osteoporosis identified as one of the commonest systemic effects of COPD. Aim The aim of this study is to delineate the association of chronic obstructive pulmonary disease (COPD) and Osteoporosis in Egyptian patients. Patients and Methods We wanted to investigate the prevalence of osteoporosis in patients with COPD as well as to correlate risk factors that increase prevalence of osteoporosis. Results Fifty patients with COPD manifestation were investigated after taking written consent for the presence of osteoporosis by spirometry examination, X-ray of the spine (for vertebral fractures), and bone mineral density (BMD) of lumbar spine and hips, parathyroid hormone luteinizing hormone follicular stimulating hormone, calcium, phosphorus, vit. D, and other lab. to exclude other secondary causes were performed. In 12 patients, X-ray revealed compression fractures previously not diagnosed. Bone density measurements showed osteoporosis in 16 patients and osteopenia in 29. Thus 80% of the patients had osteoporosis or osteopenia. Conclusion There is a significant need to initiate early prophylaxis and prevention from osteoporosis in patients with Chronic Obstructive Pulmonary Disease (COPD).

Keywords

• BMD
• COPD
• DEXA
• osteoporosis
• vertebral fractures