THE CONTRIBUTION OF KINETIC THERAPY IN LOBSTEIN’S DISEASE
Abstract
Osteogenesis imperfecta is a genetic disease of the connective tissue whose main clinical sign is increased bone fragility, manifested especially through fractures of the long limbs. OI presents major clinical signs and minor clinical signs. a). Major clinical manifestations: skeletal deformities, blue sclera, dentinogenesis imperfecta (fragile and opalescent teeth). b). Minor clinical manifestations: generalized ligamentous laxity, hernias, muscular hypotonia, hyperhidrosis, bruises that are frequent and appearing after minimum trauma. At the moment the treatment of OI. falls into the following coordinates: 1. kinetic therapy; medical recovery; 2. medical treatment-treatment with aminobiphosphonates (aredia and nerixia); 3. orthopedic and surgical treatment of the fractures and bone deformities; 4. mesenchymal stem cell transplant from the red marrow.
