mBio (Apr 2021)

One versus Many: Polymicrobial Communities and the Cystic Fibrosis Airway

  • Fabrice Jean-Pierre,
  • Arsh Vyas,
  • Thomas H. Hampton,
  • Michael A. Henson,
  • George A. O’Toole

DOI
https://doi.org/10.1128/mBio.00006-21
Journal volume & issue
Vol. 12, no. 2

Abstract

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Culture-independent studies have revealed that chronic lung infections in persons with cystic fibrosis (pwCF) are rarely limited to one microbial species. Interactions among bacterial members of these polymicrobial communities in the airways of pwCF have been reported to modulate clinically relevant phenotypes.