Clinicopathological findings of solid pseudopapillary neoplasm in a 10-year-old girl presenting with pruritus, a case report and concise review

Abstract

Solid pseudopapillary neoplasms (SPNs) are rare cystic lesions with low malignant potential making up approximately 2–3% of all primary pancreatic neoplasms in both pediatric and adult patients combined. While malignant pancreatic tumors are extremely rare in children, SPNs are one of the more common pancreatic neoplasms in this age group. Although most SPNs have a benign course with excellent long-term prognosis, they do have the potential to behave aggressively. Most children with SPN present with a palpable abdominal mass or abdominal pain. Here we describe an unusual presentation of SPN in a pediatric patient who did not have either of these findings but instead presented only with a two-month history of pruritus. We incorporate clinical, imaging, cytologic, and histologic data to make an accurate diagnosis of SPN in a 10-year-old female with an unusual presentation. Review of the literature failed to find a similar presentation of this tumor.

Keywords

• Solid pseudopapillary neoplasm
• Solid pseudopapillary tumor
• Pediatric pancreatic neoplasm
• SPN
• Pancreatic tumor
• Cystic lesion of the pancreas