npj Primary Care Respiratory Medicine (Mar 2023)

Application of an algorithm to analyze patterns of intermittent oral corticosteroid use in asthma

  • John Haughney,
  • Trung N. Tran,
  • Heath Heatley,
  • Arnaud Bourdin,
  • Andrew Menzies-Gow,
  • David J. Jackson,
  • Ekaterina Maslova,
  • Jatin Chapaneri,
  • Derek Skinner,
  • Victoria Carter,
  • Jeffrey Shi Kai Chan,
  • David Price

DOI
https://doi.org/10.1038/s41533-023-00331-0
Journal volume & issue
Vol. 33, no. 1
pp. 1 – 5

Abstract

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Abstract An algorithm to describe patterns of intermittent oral corticosteroid use in the UK (n = 476,167) found that one-third of patients receiving intermittent oral corticosteroids for asthma only had short gaps (<90 days) between oral corticosteroid prescriptions sometime during follow-up. The increasing frequency pattern was more likely in patients with greater asthma severity and with more short-acting β2-agonist use at baseline. Our approach may provide a clinically relevant representation of intermittent oral corticosteroid use in asthma.