Frontiers in Global Women's Health (Oct 2021)

Characterizing the Brain Structural Adaptations Across the Motherhood Transition

  • Magdalena Martínez-García,
  • Magdalena Martínez-García,
  • María Paternina-Die,
  • María Paternina-Die,
  • Manuel Desco,
  • Manuel Desco,
  • Manuel Desco,
  • Manuel Desco,
  • Oscar Vilarroya,
  • Oscar Vilarroya,
  • Susanna Carmona,
  • Susanna Carmona

DOI
https://doi.org/10.3389/fgwh.2021.742775
Journal volume & issue
Vol. 2

Abstract

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Women that become mothers face notable physiological adaptations during this life-period. Neuroimaging studies of the last decade have provided grounded evidence that women's brains structurally change across the transition into motherhood. The characterization of this brain remodeling is currently in its early years of research. The current article reviews this scientific field by focusing on our longitudinal (pre-to-post pregnancy) Magnetic Resonance Imaging (MRI) studies in first-time parents and other longitudinal and cross-sectional studies of parents. We present the questions that are currently being answered by the parental brain literature and point out those that have not yet been explored. We also highlight potential confounding variables that need to be considered when analyzing and interpreting brain changes observed during motherhood.

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