Effect of iron dextran injections on some synovia markers of Iraqi sport horses

Abstract

In the past decades, many veterinarians and trainers had been tried to use iron preparations as performance enhancers for racing, or for treatments such as ˝anemiȁ. The study was conducted on (12) Iraqi sport horses. The principal aims of the study were to investigate the effect of iron dextran on some synovial fluid constituents at the rest and the endurance exercise of Iraqi sports horses. The physical markers of synovial fluids of the sports horses which are included in this study, shows: (TG-1) (gallop and iron dextran treatment) are mostly slight turbid, dark yellow, very low viscid, and normal mucin clot formation. (TG-2) (Iron dextran only) are mostly clear, yellow, viscid and normal mucin clot formation. While (CG-3) (distil water only) are mostly clear, pale yellow, viscid and fair mucin clot formation. The effect of iron dextran on some biochemical markers of the synovial fluid constituents of the sports horses which included in the study were shows as in table-3: the PH value of (TG-1) was very low than normal 6.15±0.85 which was significantly different at P≤0.05 with the PH value of the (TG-2) 6.64±0.36 while the PH of (CG-3) was within normal value 7.57±0.85 and there was no significant different at P≤0.05 with (TG-2). The WBC value of (TG-1) was 8.61±0.38 (WBC/mm3) which was different significantly at P≤0.05 with (TG-2) 6.95±0.60 (WBC/mm3) but (TG-2) was not different significantly at P≤0.05 with (CG-3) 5.45±0.20. (WBC/mm3).The glucose value of (TG-1) was reduced than normal 52.89±1.58 (mg/dl), which was different significantly, at (P≤0.05) with (TG-2) 51.48±1.12 (mg/dl), but (TG-2) was not different significantly at (P≤0.05) with (CG-3) 53.14±1.04 (mg/dl). The total protein value of (TG-1) was increased than normal 3.68±0.38 (g/dl) which was different significantly at P≤0.05 with (TG-2) 2.45±0.23(g/dl) but (TG-2) was not different significantly at (P≤0.05) with (CG-3) 1.52±0.21. (g/dl). The hyaluronic acid values were significantly different at P≤0.05 between all groups, (TG-1) 0.33±0.03 (mg/ml), (TG-2) 0.21±0.03 (mg/ml), and (CG-3) 0.37±0.03 (mg/ml) respectively. The alkaline phosphatase values also were significantly different at P≤0.05 between all groups, (TG-1) 38.44±1.61 (IU/L), (TG-2) 27.25±0.22 (IU/L), and (CG-3) 25.31±1.79 (IU/L), respectively. In conclusion, iron injections had no any improvement to the sport horses' synovia.