PLoS Medicine (Nov 2021)

Epidemiology of type 2 diabetes remission in Scotland in 2019: A cross-sectional population-based study.

  • Mireille Captieux,
  • Kelly Fleetwood,
  • Brian Kennon,
  • Naveed Sattar,
  • Robert Lindsay,
  • Bruce Guthrie,
  • Sarah H Wild,
  • Scottish Diabetes Research Network Epidemiology Group

DOI
https://doi.org/10.1371/journal.pmed.1003828
Journal volume & issue
Vol. 18, no. 11
p. e1003828

Abstract

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BackgroundClinical pathways are changing to incorporate support and appropriate follow-up for people to achieve remission of type 2 diabetes, but there is limited understanding of the prevalence of remission in current practice or patient characteristics associated with remission.Methods and findingsWe carried out a cross-sectional study estimating the prevalence of remission of type 2 diabetes in all adults in Scotland aged ≥30 years diagnosed with type 2 diabetes and alive on December 31, 2019. Remission of type 2 diabetes was assessed between January 1, 2019 and December 31, 2019. We defined remission as all HbA1c values ConclusionsIn this study, we found that 4.8% of people with type 2 diabetes who had at least 1 HbA1c ≥48 mmol/mol (6.5%) after diagnosis of diabetes and had at least 1 HbA1c recorded in 2019 had evidence of type 2 diabetes remission. Guidelines are required for management and follow-up of this group and may differ depending on whether weight loss and remission of diabetes were intentional or unintentional. Our findings can be used to evaluate the impact of future initiatives on the prevalence of type 2 diabetes remission.