Case report: Corticosteroids as an adjunct treatment for the management of liver abscess in Papillon–Lefèvre syndrome: A report on two cases

Suprit Basu; Reva Tyagi; Ankur Kumar Jindal; Apurva Medha; Aaqib Zaffar Banday; Alisha Babbar; Apoorva Sharma; Rahul Mahajan; Pandiarajan Vignesh; Amit Rawat

doi:10.3389/fped.2022.953033

Frontiers in Pediatrics (Sep 2022)

Case report: Corticosteroids as an adjunct treatment for the management of liver abscess in Papillon–Lefèvre syndrome: A report on two cases

Suprit Basu,
Reva Tyagi,
Ankur Kumar Jindal,
Apurva Medha,
Aaqib Zaffar Banday,
Alisha Babbar,
Apoorva Sharma,
Rahul Mahajan,
Pandiarajan Vignesh,
Amit Rawat

Affiliations

Suprit Basu: Pediatric Allergy Immunology Unit, Department of Pediatrics, Postgraduate Institute of Medical Education and Research, Chandigarh, India
Reva Tyagi: Pediatric Allergy Immunology Unit, Department of Pediatrics, Postgraduate Institute of Medical Education and Research, Chandigarh, India
Ankur Kumar Jindal: Pediatric Allergy Immunology Unit, Department of Pediatrics, Postgraduate Institute of Medical Education and Research, Chandigarh, India
Apurva Medha: Pediatric Allergy Immunology Unit, Department of Pediatrics, Postgraduate Institute of Medical Education and Research, Chandigarh, India
Aaqib Zaffar Banday: Pediatric Allergy Immunology Unit, Department of Pediatrics, Postgraduate Institute of Medical Education and Research, Chandigarh, India
Alisha Babbar: Pediatric Allergy Immunology Unit, Department of Pediatrics, Postgraduate Institute of Medical Education and Research, Chandigarh, India
Apoorva Sharma: Department of Dermatology, Venereology and Leprology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
Rahul Mahajan: Department of Dermatology, Venereology and Leprology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
Pandiarajan Vignesh: Pediatric Allergy Immunology Unit, Department of Pediatrics, Postgraduate Institute of Medical Education and Research, Chandigarh, India
Amit Rawat: Pediatric Allergy Immunology Unit, Department of Pediatrics, Postgraduate Institute of Medical Education and Research, Chandigarh, India

DOI: https://doi.org/10.3389/fped.2022.953033
Journal volume & issue: Vol. 10

Abstract

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Papillon–Lefèvre syndrome (PLS) is a rare autosomal recessive disorder characterized clinically by palmoplantar keratoderma, periodontitis, and recurrent pyogenic infections. Liver abscess is rarely reported in patients. The use of corticosteroids for the treatment of liver abscess akin to chronic granulomatous disease (CGD) has not been reported previously. Here, we report 2 cases of liver abscess in PLS that responded to corticosteroids.

Published in Frontiers in Pediatrics

ISSN: 2296-2360 (Online)
Publisher: Frontiers Media S.A.
Country of publisher: Switzerland
LCC subjects: Medicine: Pediatrics
Website: http://journal.frontiersin.org/journal/pediatrics

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