Sarcoma
(Jan 2002)
Absence of Telomerase Activity in Malignant Bone Tumors and Soft-Tissue
Sarcomas
Nina K. Lauer,
Sandra M. Maier,
Martin Oberringer,
Michael Schulte,
Wolf Mutschler,
Rainer G. Hanselmann,
Manfred Schartl,
Stefan J. Scherer,
Reiner J. Wirbel
Affiliations
Nina K. Lauer
Department of Reconstructive Surgery, University of Saarland, Homburg/Saar D-66421, Germany
Sandra M. Maier
Department of Human Genetics, University of Saarland, Geb. 68, Homburg/Saar D-66421, Germany
Martin Oberringer
Department of Experimental Physics, University of Saarland, Geb. 22, Saarbrücken 68111, Germany
Michael Schulte
Department of Experimental Physics, University of Saarland, Geb. 22, Saarbrücken 68111, Germany
Wolf Mutschler
Department of Surgery, Ludwig Maximillian-University of Munich, Klinikum Innenstadt, Munich 80336, Germany
Rainer G. Hanselmann
Department of Experimental Physics, University of Saarland, Geb. 22, Saarbrücken 68111, Germany
Manfred Schartl
Department of Physiological Chemistry I, Biocenter, University of Wuerzburg, Wuerzburg 97074, Germany
Stefan J. Scherer
Department of Physiological Chemistry I, Biocenter, University of Wuerzburg, Wuerzburg 97074, Germany
Reiner J. Wirbel
Department of Surgery, Elisabeth-Hospital, Neuwied 56564, Germany
DOI
https://doi.org/10.1080/13577140220127549
Journal volume & issue
Vol. 6,
no. 1
Abstract
Read online
Purpose: Telomerase activity appears to play a crucial role in the development of many tumors. More than 80% of all malignant human tumors show an increased telomerase activity. However, conflicting results have been reported about telomerase activity in sarcomas. The aim of the study was to obtain more information about telomerase activity in sarcomas based on a large number of cases.
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