Increased levels of neurofilament light chain in suicide attempters’ serum

Abstract

A specific biological vulnerability underlies suicidal behavior. Recent findings have suggested a possible role of inflammation and neuroaxonal injury. However, the relationship between inflammation and clinical symptoms in this disorder is still unclear. The objective of this study is applying novel blood markers of neuroaxonal integrity such as neurofilament light chain (NfL) and comparing the results with the healthy control subjects.

Keywords

• neurofilament light chain
• suicidal ideation
• inflammation
• axonal damage