Disease Models & Mechanisms (Nov 2023)
A Drosophila model targets Eiger/TNFα to alleviate obesity-related insulin resistance and macrophage infiltration
- Zhasmine Mirzoyan,
- Alice Valenza,
- Sheri Zola,
- Carola Bonfanti,
- Lorenzo Arnaboldi,
- Nicholas Ferrari,
- John Pollard,
- Valeria Lupi,
- Matteo Cassinelli,
- Matteo Frattaroli,
- Mehtap Sahin,
- Maria Enrica Pasini,
- Paola Bellosta
Affiliations
- Zhasmine Mirzoyan
- Department of Computational, Cellular and Integrative Biology (CIBIO), University of Trento, 38123 Trento, Italy
- Alice Valenza
- Department of Biosciences, University of Milan, 20133 Milan, Italy
- Sheri Zola
- Department of Computational, Cellular and Integrative Biology (CIBIO), University of Trento, 38123 Trento, Italy
- Carola Bonfanti
- Department of Biosciences, University of Milan, 20133 Milan, Italy
- Lorenzo Arnaboldi
- Department of Pharmacology, University of Milan, 20133 Milan, Italy
- Nicholas Ferrari
- Department of Computational, Cellular and Integrative Biology (CIBIO), University of Trento, 38123 Trento, Italy
- John Pollard
- Department of Biosciences, University of Milan, 20133 Milan, Italy
- Valeria Lupi
- Department of Biosciences, University of Milan, 20133 Milan, Italy
- Matteo Cassinelli
- Department of Biosciences, University of Milan, 20133 Milan, Italy
- Matteo Frattaroli
- Department of Biosciences, University of Milan, 20133 Milan, Italy
- Mehtap Sahin
- Department of Computational, Cellular and Integrative Biology (CIBIO), University of Trento, 38123 Trento, Italy
- Maria Enrica Pasini
- Department of Biosciences, University of Milan, 20133 Milan, Italy
- Paola Bellosta
- Department of Computational, Cellular and Integrative Biology (CIBIO), University of Trento, 38123 Trento, Italy
- DOI
- https://doi.org/10.1242/dmm.050388
- Journal volume & issue
-
Vol. 16,
no. 11
Abstract
No abstracts available.Keywords
- drosophila model
- adipose chronic inflammation
- eiger/tnfα signaling
- insulin resistance
- lipid metabolism
- obesity
- metabolic disorders
