Analysis

Abstract

Aim of the work: This study aimed to analyze induced sputum in asthmatic patients under different forms of treatment and study factors that may affect sputum cellularity in asthmatic patients. Patients and methods: Eighty asthmatic patients were included. Patients with contra-indication for sputum induction were excluded. Spirometer, sputum induction, sputum processing, sputum total cell count, viability, centrifugation, staining and count were done. Results: Eighty patients were included in the study to investigate induced sputum in asthmatic patients under different forms of treatment. Patient’s sex 43 (53.8%) male and 37 (46.2%) female patients were included. Their mean age ± SD was 32.05 ± 10.87 years. Sputum cell indices of asthmatic patients were 35.22% neutrophilic inflammation, 17.81% eosinophilic inflammation and the lymphocytic inflammation was 26.48%. Conclusion: Study concluded that the use of sputum induction as noninvasive measurements of airway inflammation in the diagnosis and management of asthma is very important for every patient diagnosed with bronchial asthma before starting asthma management and for asthmatic patients who were not controlled by full asthma management to understand the type of airway inflammation.

Keywords

• Bronchial asthma
• Sputum induction
• ICS
• Sputum cell count