Nature Communications (Nov 2022)

Gating and ion selectivity of Channelrhodopsins are critical for photo-activated orientation of Chlamydomonas as shown by in vivo point mutation

  • Olga Baidukova,
  • Johannes Oppermann,
  • Simon Kelterborn,
  • Rodrigo G. Fernandez Lahore,
  • Dimitri Schumacher,
  • Heide Evers,
  • Yousef Yari Kamrani,
  • Peter Hegemann

DOI
https://doi.org/10.1038/s41467-022-35018-6
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 13

Abstract

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Channelrhodopsin photoreceptors are responsible for phototaxis in C. reinhardtii. Here, authors introduce point mutations in the channel which modify photocycle kinetics and ion selectivity, resulting in a deeper understanding of phototaxis in low light conditions.