A sonochemical synthesis of SrTiO3 supported N-doped graphene oxide as a highly efficient electrocatalyst for electrochemical reduction of a chemotherapeutic drug

Umamaheswari Rajaji; M.S. Raghu; K. Yogesh Kumar; Tahani M. Almutairi; AbdallahA.A. Mohammed; Ruey-Shin Juang; Ting-Yu Liu

Ultrasonics Sonochemistry (Feb 2023)

A sonochemical synthesis of SrTiO3 supported N-doped graphene oxide as a highly efficient electrocatalyst for electrochemical reduction of a chemotherapeutic drug

Umamaheswari Rajaji,
M.S. Raghu,
K. Yogesh Kumar,
Tahani M. Almutairi,
AbdallahA.A. Mohammed,
Ruey-Shin Juang,
Ting-Yu Liu

Affiliations

Umamaheswari Rajaji: Department of Materials Engineering, Ming Chi University of Technology, New Taipei City 243303, Taiwan
M.S. Raghu: Department of Chemistry, New Horizon College of Engineering, Outer Ring Road, Bangalore 560103, India
K. Yogesh Kumar: Department of Chemistry, Faculty of Engineering and Technology, Jain University, Bangalore 562112, India; Korea University of Technology and Education, Cheonan-si 31253, Chungcheongnam-do, Cheonan-si, Republic of Korea
Tahani M. Almutairi: Chemistry Department, College of Science, King Saud University, Riyadh 11451, Saudi Arabia
AbdallahA.A. Mohammed: Chemistry Department, College of Science, King Saud University, Riyadh 11451, Saudi Arabia
Ruey-Shin Juang: Department of Chemical and Materials Engineering, Chang Gung University 259 Wenhua First Road Guishan, Taoyuan 33302, Taiwan; Division of Nephrology, Department of Internal Medicine, Chang Gung Memorial Hospital, Linkou, Taiwan; Department of Safety, Health and Environmental Engineering, Ming Chi University of Technology, Taishan, New Taipei City 243303, Taiwan; Corresponding authors at: Department of Chemical and Materials Engineering, Chang Gung University 259 Wenhua First Road Guishan, Taoyuan 33302, Taiwan.
Ting-Yu Liu: Department of Materials Engineering, Ming Chi University of Technology, New Taipei City 243303, Taiwan; Research Center for Intelligent Medical Devices, Center for Plasma and Thin Film Technologies, Ming Chi University of Technology, New Taipei City 243303, Taiwan; Corresponding authors at: Department of Chemical and Materials Engineering, Chang Gung University 259 Wenhua First Road Guishan, Taoyuan 33302, Taiwan.

Journal volume & issue: Vol. 93
p. 106293

Abstract

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A sonochemical based green synthesis method playa powerful role in nanomaterials and composite development. In this work, we developed a perovskite type of strontium titanate via sonochemical process. SrTiO3 particles were incorporated with nitrogen doped graphene oxide through simple ultrasonic irradiation method. The SrTiO3/NGO was characterized by various analytical methods. The nanocomposite of SrTiO3/NGO was modified with laser-induced graphene electrode (LIGE). The SrTiO3/NGO/LIGE was applied for electrochemical sensor towards chemotherapeutic drug detection (nilutamide). Cyclic voltammetry (CV) and differential pulse voltammetry (DPV) techniques have been used to examine the electrochemical performance of nilutamide (anti-cancer drug). DPV was found to be more sensitive and found to exhibit a sensitivity 8.627 µA µM−1 cm−2 for SrTiO3/NGO/LIGE with a wide linear range (0.02–892 µM) and low Limit of detection (LOD: 1.16 µM). SrTiO3/NGO/LIGE has been examined for the detection of nilutamide in blood serum and urine samples and obtained a good recovery in the range of 97.2–99.72 %. The enhanced stability and selectivity and practical application results indicates the suitability of SrTiO3/NGO/LIGE towards the detection of nilutamide drug in pharmaceutical industries.

Published in Ultrasonics Sonochemistry

ISSN: 1350-4177 (Print); 1873-2828 (Online)
Publisher: Elsevier
Country of publisher: Netherlands
LCC subjects: Science: Chemistry; Science: Physics: Acoustics. Sound
Website: https://www.journals.elsevier.com/ultrasonics-sonochemistry

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