Human transcription factor protein interaction networks

Helka Göös; Matias Kinnunen; Kari Salokas; Zenglai Tan; Xiaonan Liu; Leena Yadav; Qin Zhang; Gong-Hong Wei; Markku Varjosalo

doi:10.1038/s41467-022-28341-5

Nature Communications (Feb 2022)

Human transcription factor protein interaction networks

Helka Göös,
Matias Kinnunen,
Kari Salokas,
Zenglai Tan,
Xiaonan Liu,
Leena Yadav,
Qin Zhang,
Gong-Hong Wei,
Markku Varjosalo

Affiliations

Helka Göös: Institute of Biotechnology, HiLIFE, University of Helsinki
Matias Kinnunen: Institute of Biotechnology, HiLIFE, University of Helsinki
Kari Salokas: Institute of Biotechnology, HiLIFE, University of Helsinki
Zenglai Tan: Biocenter Oulu and Faculty of Biochemistry and Molecular Medicine, University of Oulu
Xiaonan Liu: Institute of Biotechnology, HiLIFE, University of Helsinki
Leena Yadav: Institute of Biotechnology, HiLIFE, University of Helsinki
Qin Zhang: Biocenter Oulu and Faculty of Biochemistry and Molecular Medicine, University of Oulu
Gong-Hong Wei: Biocenter Oulu and Faculty of Biochemistry and Molecular Medicine, University of Oulu
Markku Varjosalo: Institute of Biotechnology, HiLIFE, University of Helsinki

DOI: https://doi.org/10.1038/s41467-022-28341-5
Journal volume & issue: Vol. 13, no. 1
pp. 1 – 16

Abstract

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Transcription factors (TFs) interact with several other proteins in the process of transcriptional regulation. Here the authors identify 6703 and 1536 protein–protein interactions for 109 different human TFs through BioID and AP-MS analyses, respectively.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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