Iodine-mediated synthesis of 3-acylbenzothiadiazine 1,1-dioxides

Abstract

An iodine-mediated synthesis of 3-acylbenzothiadizine 1,1-dioxides is described. A range of electronically diverse acetophenones reacted well with several 2-aminobenzenesulfonamides, affording 3-acylbenzothiadiazine 1,1-dioxides in good yields.

Keywords

• 3-acylbenzothiadiazine 1,1-dioxides
• cyclization
• metal-free
• oxidation