Renal Transplantation in Autosomal Dominant Polycystic Kidney Disease

Abstract

Autosomal dominant polycystic kidney disease (ADPKD) affects approximately 1 in 1,000 people in the general population. The natural history of ADPKD includes the progression of chronic kidney disease to end-stage renal disease (ESRD) in a large proportion of patients. Renal transplantation is the treatment modality of choice in these patients. However, there are some specific issues that should be addressed in ADPKD, and the aim of the current review is to describe the issues that need to be considered in the pre and post-transplant management of ADPKD patients, excluding routine procedures.

Keywords

• Autosomal dominant polycystic kidney disease
• intracranial aneurysms
• native nephrectomy