G3: Genes, Genomes, Genetics (Nov 2022)

Impact of antibiotic perturbation on fecal viral communities in mice

  • Jacqueline Moltzau Anderson,
  • Tim Lachnit,
  • Simone Lipinski,
  • Maren Falk-Paulsen,
  • Philip Rosenstiel

DOI
https://doi.org/10.1093/g3journal/jkac293
Journal volume & issue
Vol. 13, no. 1

Abstract

Read online

AbstractViruses and bacteriophages have a strong impact on intestinal barrier function and the composition and functional properties of commensal bacterial communities. Shifts of the fecal virome might be involved in human diseases, including inflammatory bowel disease (IBD). Loss-of-function variants in the nucleotide-binding oligomerization domain-containing protein 2 (NOD2C57BL/6JNOD2