CHIMIA (Oct 2020)

The 'Holy Grail' in Immuno-Oncology: AC BioScience SA is Aiming to Potentiate Anti-PD-1 Therapy Efficacy through Tumor Cell Conditioning Strategy

  • Andreas Schläpfer,
  • Christian Auclair,
  • Bassam Janji,
  • Manuel Karam,
  • Muhammad Zaeem Noman

DOI
https://doi.org/10.2533/chimia.2020.771
Journal volume & issue
Vol. 74, no. 10
pp. 771 – 775

Abstract

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AC BioScience is a Swiss biotech company based at the EPFL Innovation Park and Biopôle, dedicated to developing groundbreaking therapies to fight a range of cancers and infectious diseases. We are about to start clinical trials with two of four leading-edge cancer drugs mainly focusing on immune-oncology and tumor vascular normalization with multi-billion $ sales potential. Here, we present our strategy and one of our pioneering drug candidates that has already shown exceptional results with tumor cell conditioning to improve the efficacy of immune checkpoint inhibitors.

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