Considerations on the treatment of Wilms’ tumor

Abstract

Introduction: Wilms’ tumor is the most common renal neoplasm in childhood, which makes it necessary to be updated in terms of its treatment. Objective: to describe the treatment of Wilms’ tumor. Method: a literature review was carried out in the Web of Science, Scopus, PubMed, ClinicalKey and SciELO databases. The search strategy used was a combination of terms, using the name of the disease and treatments. Twenty-six references were chosen. Development: Wilms’ tumor represents a malignant tumor with a high cure rate; which is possible thanks to the development of surgical techniques, application of chemotherapy and recognition of the role of radiotherapy. These techniques used rationally have a great impact on the survival rate to this neoplasm. A fundamental pillar in the management of this entity is nephrectomy. There are two positions according to the moment of treatment with chemotherapy; before and after the surgical procedure. Radiotherapy is another modality in the treatment of nephroblastoma; it is used in advanced stages or in conditions where there are associated risk factors. Conclusions: the treatment of Wilms’ tumor depends on the histological classification and staging. Its treatment is multidisciplinary and includes the combination of surgery, chemotherapy and radiotherapy. The application of the existing therapeutic protocols, as long as the parameters they establish are maintained, will have successful results in spite of the different sequences in which the therapeutic modalities are used.

Keywords

• tumor de wilms
• neoplasias renales
• nefrectomía
• asistentes de pediatría.