Nanoparticles for imaging-guided photothermal therapy of colorectal cancer
Omid Rahbar Farzam,
Niloofar Mehran,
Farzaneh Bilan,
Ehsan Aghajani,
Reza Dabbaghipour,
Ghazale Asemani Shahgoli,
Behzad Baradaran
Affiliations
Omid Rahbar Farzam
Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran; Department of Medical Biotechnology, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran; Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
Niloofar Mehran
Clinical Research Development Unit, Imam Reza General Hospital, Tabriz University of Medical Sciences, Tabriz, Iran
Farzaneh Bilan
Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
Ehsan Aghajani
Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
Reza Dabbaghipour
Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran; Department of Medical Genetics, Shiraz University of Medical Sciences, Shiraz, Iran; Clinical Research Development Unit, Imam Reza General Hospital, Tabriz University of Medical Sciences, Tabriz, Iran
Ghazale Asemani Shahgoli
Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
Behzad Baradaran
Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran; Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran; Corresponding author. Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Colorectal cancer (CRC) is one of the most common malignancies with a high mortality rate worldwide. While surgery, chemotherapy, and radiotherapy have shown some effectiveness in improving survival rates, they come with drawbacks such as side effects and harm to healthy tissues. The theranostic approach, which integrates the processes of cancer diagnosis and treatment, can minimize biological side effects. Photothermal therapy (PTT) is an emerging treatment method that usages light-sensitive agents to generate heat at the tumor site and induce thermal erosion. The development of nanotechnology for CRC treatment using imaging-guided PTT has garnered significant. Nanoparticles with suitable physical and chemical properties can enhance the efficiency of cancer diagnosis and PTT. This approach enables the monitoring of cancer treatment progress and safeguards healthy tissues. In this article, we concisely introduce the application of metal nanoparticles, polymeric nanoparticles, and carbon nanoparticles in imaging-guided PTT of colorectal cancer.
