Inhibitory Circuits in the Basolateral Amygdala in Aversive Learning and Memory

Madhusoothanan B. Perumal; Pankaj Sah; Pankaj Sah; Pankaj Sah

doi:10.3389/fncir.2021.633235

Frontiers in Neural Circuits (Apr 2021)

Inhibitory Circuits in the Basolateral Amygdala in Aversive Learning and Memory

Madhusoothanan B. Perumal,
Pankaj Sah,
Pankaj Sah,
Pankaj Sah

Affiliations

Madhusoothanan B. Perumal: Queensland Brain Institute, The University of Queensland, Brisbane, QLD, Australia
Pankaj Sah: Queensland Brain Institute, The University of Queensland, Brisbane, QLD, Australia
Pankaj Sah: Joint Center for Neuroscience and Neural Engineering, Southern University of Science and Technology, Shenzhen, China
Pankaj Sah: Department of Biology, Southern University of Science and Technology, Shenzhen, China

DOI: https://doi.org/10.3389/fncir.2021.633235
Journal volume & issue: Vol. 15

Abstract

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Neural circuits in the basolateral amygdala (BLA) play a pivotal role in the learning and memory formation, and processing of emotionally salient experiences, particularly aversive ones. A diverse population of GABAergic neurons present in the BLA orchestrate local circuits to mediate emotional memory functions. Targeted manipulation of GABAergic neuronal subtypes has shed light on cell-type specific functional roles in the fear learning and memory, revealing organizing principles for the operation of inhibitory circuit motifs in the BLA.

Published in Frontiers in Neural Circuits

ISSN: 1662-5110 (Online)
Publisher: Frontiers Media S.A.
Country of publisher: Switzerland
LCC subjects: Medicine: Internal medicine: Neurosciences. Biological psychiatry. Neuropsychiatry
Website: https://www.frontiersin.org/journals/neural-circuits/

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Abstract

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