Journal of Physical Fitness and Sports Medicine (Jun 2013)

Effects of exercise on glucagon-like peptide-1 (GLP-1)

  • Shin-ya Ueda,
  • Hidehiro Nakahara,
  • Tadayoshi Miyamoto

DOI
https://doi.org/10.7600/jpfsm.2.221
Journal volume & issue
Vol. 2, no. 2
pp. 221 – 224

Abstract

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Appetite and eating behaviour are controlled by a variety of peripheral signals that change in response to food intake and act in the hypothalamus and brainstem. Glucagon-like peptide-1 (GLP-1) is a brain-gut peptide that has a variety of physiological functions and is involved in appetite regulation. Abnormalities in the expression and secretion of GLP-1 have been shown to occur in obesity, diabetes, and hyperlipidemia, and improving these abnormalities has become an important challenge. Exercise has recently been shown to have an influence on GLP-1 concentrations. This short review aims to highlight the association between exercise and the blood kinetics of GLP-1 and discuss the relevance of GLP-1 in the regulation of appetite to prevent obesity.

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