Epidermolysis bullosa acquisita following skin graft in donor and graft sites: A case report
Joyce Xia,
Alice J. Tan,
Gunnlaugur P. Nielsen,
Ruth K. Foreman,
Mai Hoang,
Sean A. Hickey,
Daniela Kroshinsky
Affiliations
Joyce Xia
Department of Dermatology, Massachusetts General Hospital, Boston, MA, USA
Alice J. Tan
Department of Dermatology, Massachusetts General Hospital, Boston, MA, USA
Gunnlaugur P. Nielsen
Harvard Medical School, Boston, MA, USA; Department of Pathology, Massachusetts General Hospital, Boston, MA, USA
Ruth K. Foreman
Harvard Medical School, Boston, MA, USA; Department of Pathology, Massachusetts General Hospital, Boston, MA, USA
Mai Hoang
Harvard Medical School, Boston, MA, USA; Department of Pathology, Massachusetts General Hospital, Boston, MA, USA
Sean A. Hickey
Harvard Medical School, Boston, MA, USA; Department of Surgery, Massachusetts General Hospital, Boston, MA, USA
Daniela Kroshinsky
Department of Dermatology, Massachusetts General Hospital, Boston, MA, USA; Harvard Medical School, Boston, MA, USA; Corresponding author at: Department of Dermatology, Massachusetts General Hospital, 50 Staniford St, Ste 200, Boston, MA 02114, USA.
Epidermolysis bullosa acquisita is a rare mucocutaneous autoimmune blistering disorder which usually presents in adulthood. The disease is mediated by antibodies against type VII collagen, though the precise inciting factors for autoantibody formation are unknown. Here, we present the case of a 69-year-old man who developed this condition following autograft. We highlight this case to draw attention to a rare cause of skin graft failure, with early referral to specialist care necessary for avoidance of sequelae related to scarring.
